Hillstream loaches like to be kept in a group (three is good). They also like a tank with lots of current and aeration. Unless most of the plecos, they are not messy fish and do not add much to the bioload of a tank.
They do need pristine water, though, and enjoy driftwood and rock formations. Also, at the beginning, they require a tank with algae since they are wild caught and are not accustomed to eating commercial fish food. After a few months, though, they do acquire a taste for most sinking pellets and will gladly eat things such as blanched zucchini