to be honest, i didnt know myself til i tried it today!
daphnia are very small waterfleas, and so they are very light. i put a half defrosted cube into my tank and peices came off quite rapidly, and floated around the tank. the fish ate them quite quickly though. eventually they will sink and end up on the floor/gravel.
if you have many fish who will eat this quickly like i do (i have a group of white cloud minnows as well as a common goldfish) then it's not really a problem as it will get eaten up quickly. if you have few fish and worry about waste a feeding dish may help (although difficult because the daphnia is small and light) or perhaps feeding small potions of the defrosted cube at a time, making sure it is all eaten before giving more, so that there is not excess food in the tank.
I have found that a whole cube is a lot of food, and have taken to half defrosting then splitting it in two, to share between my two tanks. but only because i have quite small tanks and fish, and obviously this depends on the size of your tank, how many fish you have, and how much they will eat.
hope this helps