HI Mags,
I change 20-30% of the water in my 46 gal, once a week. I also vacuum the gravel, if you don't toxins can build up in the gravel and then when you do vacuum it, the toxins are released into the water and will hurt the fish.
As long as you have a cycled tank, and don't clean the filter everytime, vacuuming is good. If you are scared of crashing your cycle then alternate when you gravel with cleaning the filter.
Testing, is a good indication as to how much water to change, so I recommend testing before and after the change.
Good luck.
PS ( I also love it here).