That is perplexing. I had a bad experience with Melafix and won't use it again. I know that most people love it and say it is a "miracle" cure but it actually burned one of my fish.
I have an orange fantail who is more sensitive and is just not as healthy as my other fish. She became very lethargic when I treated the tank with Melafix for her torn tail. It didn't help so I did a huge water change, added back charcoal and she turned almost completely black! She looked like someone handled her with motor oil. The black is healing tissue after whatever has caused the problem is gone.
Her tail finally got better on its own and grew back. A big chunk of it was missing.
I don't know what to suggest to you since your water params are fine. Just keep up with 25% weekly water changes. And some fish are affected by their genetics. no matter how excellent the care we can give them.